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Search Results for " sonic hedgehog "

Targets

7

Compounds

11

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T22089 HPI 1 Hedgehog/Smoothened
HPI 1 is a hedgehog (Hh) signaling inhibitor. Inhibits Sonic hedgehog (Shh)-, SAG- and Gli-induced Hh pathway activation in Shh-LIGHT2 cells (IC50 values are 1.5, 1.5, 4, and 6 μM for Shh-, SAG-, Gli2- and Gli1-induced a...
T26899 BRD50837 BRD-50837,BRD 50837
BRD50837 is a potent and selective inhibitor of Sonic Hedgehog (Shh).
T26901 BRD-9526 BRD 9526
BRD-9526 is a potent and selective inhibitor of Sonic Hedgehog (Shh).
T23307 SANT 2 SANT-2 Others
SANT-2 is an inhibitor of Sonic hedgehog signaling and also antagonizes smoothened receptor activity (KD = 12 nM).
T25918 Palmitoyl-L-aspartic acid L-N-Palmitoylaspartic acid
Palmitoyl-L-aspartic acid is a natural N-acylaspartate that suppresses Hedgehog signaling after stimulation with Smoothened agonist or non-sterol-modified Sonic Hedgehog. It does not alter the activity of cannabinoid rec...
T35538 HPI-1 (hydrate) HPI-1 hydrate
HPI-1 (hydrate) is a Hedgehog (Hh) pathway inhibitor that suppresses signaling through Sonic Hh (IC50= 1.5 μM) without significantly affecting Wnt signaling (IC50≥ 30 μM).1HPI-1 suppresses Hh activation induced by loss o...
T35940 Darinaparsin Dimethylarsinic glutathione,Darinaparsin
Darinaparsin is a dimethylated arsenic linked to glutathione. It is cytotoxic to DU145, LNCaP, and PC3 prostate cancer cells (IC50s = 5-10 &#181M) and patient-derived primary prostate cancer cells (IC50s = 2.5-20 &#181M)...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-03345 Sonic Hedgehog Protein, Mouse, Recombinant (His) Mouse HEK293
Sonic HedgeHog, also known as sonic hedgehog protein, belongs to the hedgehog family. It cannot be detected in adult tissues while can be found in fetal intestine, liver, lung, and kidney. Sonic HedgeHog is a protein tha...
TMPJ-01170 SHH Protein, Mouse, Recombinant Mouse E. coli
Mouse Sonic Hedgehog Homolog (SHH) belongs to a three-protein family called Hedgehog. The other two family members are Indian Hedgehog (IHH) and Desert Hedgehog (DHH). Hedgehog proteins are key signaling molecules in emb...
TMPJ-01171 SHH Protein, Mouse, Recombinant (C25II) Mouse E. coli
Mouse Sonic Hedgehog Homolog (SHH) belongs to a three-protein family called Hedgehog. The other two family members are Indian Hedgehog (IHH) and Desert Hedgehog (DHH). Hedgehog proteins are key signaling molecules in emb...
TMPJ-01128 SHH Protein, Human, Recombinant (C24II) Human E. coli
Sonic Hedgehog Homolog (SHH) belongs to a three-protein family called Hedgehog. The other two family members are Indian Hedgehog (IHH) and Desert Hedgehog (DHH). Hedgehog proteins are key signaling molecules in embryonic...
TMPJ-01127 SHH Protein, Human, Recombinant Human E. coli
Sonic Hedgehog Homolog (SHH) belongs to a three-protein family called hedgehog. The other two family members are Indian Hedgehog (IHH) and Desert Hedgehog (DHH). Hedgehog proteins are key signaling molecules in embryonic...
TMPY-02832 SHH Protein, Human, Recombinant (aa 198-462, His) Human HEK293
Sonic HedgeHog, also known as sonic hedgehog protein, belongs to the hedgehog family. It cannot be detected in adult tissues while can be found in fetal intestine, liver, lung, and kidney. Sonic HedgeHog is a protein tha...
TMPY-02905 SHH Protein, Human, Recombinant (aa 1-197, His) Human HEK293
Sonic HedgeHog, also known as sonic hedgehog protein, belongs to the hedgehog family. It cannot be detected in adult tissues while can be found in fetal intestine, liver, lung, and kidney. Sonic HedgeHog is a protein tha...
TMPY-00804 FGF-9 Protein, Human, Recombinant (hFc) Human HEK293
Fibroblast growth factor 9 (FGF9) also known as Glia-activating factor or Heparin-binding growth factor 9, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell sur...
TMPY-04085 FGF-9 Protein, Canine, Recombinant (mFc) Canine HEK293
Fibroblast growth factor 9 (FGF9) also known as Glia-activating factor or Heparin-binding growth factor 9, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell sur...
TMPY-02384 MTSS1 Protein, Human, Recombinant (aa1-250, His & MBP) Human E. coli
MTSS1 (Metastasis suppressor 1), also known as Missing in metastasis (MIM), is a tissue-specific regulator of plasma membrane dynamics. MTSS1 is well described for its function as a metastasis suppressor gene and is expr...
TMPH-01616 LRP2 Protein, Human, Recombinant (mFc) Human HEK293
Multiligand endocytic receptor. Acts together with CUBN to mediate endocytosis of high-density lipoproteins. Mediates receptor-mediated uptake of polybasic drugs such as aprotinin, aminoglycosides and polymyxin B. In the...
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